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Tet2 loss dysregulates the behavior of bone marrow derived mesenchymal stromal cells [hME-Seal]

NIAID Data Ecosystem2026-05-25 收录

细胞表观遗传学

Tet2基因功能

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP109568 数据链接链接失效反馈

官方服务：

资源简介：

Identification the genome-wide distribution of 5-hmC in WT-MSCs and Tet2-/--MSCs by Genome-wide 5hmc Profiling. Overall design: Identification the genome-wide distribution of 5-hmC in WT-MSCs and Tet2-/--MSCs by Genome-wide 5hmc Profiling.

应用场景：

创建时间：

2018-02-15

细胞表观遗传学

ChIP-seq数据分析

Histone modifications have been shown critically involved in transcriptional regulation, but the functions of histone modifiers and the impact of histone modifications in early transcription induction

NIAID Data Ecosystem30

ATACseq of human basophils, B cells and CD34-derived basophils. ATACseq of human basophils, B cells and CD34-derived basophils

细胞表观遗传学

染色质可及性分析

human basophils and B cells (that were purified to >98% homogeneity) and CD34-derived basophils were processed for ATACseq Overall design: 100,000 to 200,000 resting cells were lysed and treated with

NIAID Data Ecosystem20

Eight in situ Hi-C experiments of mouse OG2 stem cells for 7 different starting material and that were digested by either HindIII (2 samples) or MboI (6 samples) restriction enzymes

染色质构象

细胞表观遗传学

In this experiment, we've examined chromatin conformation of OG2 (B6; CBA-Tg(Pou5f1-EGFP)2Mnn/J; stock number 004654) mouse stem cells cultured as described in (Shi et al., 2008), using different amou

NIAID Data Ecosystem10

Flicr, a long noncoding RNA modulating Foxp3 expression and autoimmunity (ATAC-Seq). Mus musculus

细胞表观遗传学

自身免疫疾病机制

ATAC-seq profiles of Tregs isolated from spleen and LN in Flicr WT and KO mice Overall design: DAPI-CD4+TCRb+ CD25hi (top 50%) Tregs were single sorted from the spleen and LN of male NOD mice and ATAC

NIAID Data Ecosystem20

NFI Transcription Factors Govern Stem Cell Chromatin Accessibility and Guard Against Irreversible Hair Loss [ATAC-seq]. NFI Transcription Factors Govern Stem Cell Chromatin Accessibility and Guard Against Irreversible Hair Loss [ATAC-seq]

细胞表观遗传学

毛发生物学

Tissue homeostasis and regeneration rely upon resident stem cells (SCs), whose behavior is regulated through niche-dependent crosstalk. The mechanisms underlying SC maintenance are still unfolding. He

NIAID Data Ecosystem10

Tet2 loss dysregulates the behavior of bone marrow derived mesenchymal stromal cells [hME-Seal]

资源简介：

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