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Crystal structure of human beta-secretase in complex with NVP-ARV999

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Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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Crystal structure of human beta-secretase in complex with NVP-ARV999 Descriptor: (2R,4S)-N-butyl-4-[(2S,5S,7R)-2,7-dimethyl-3,15-dioxo-1,4-diazacyclopentadecan-5-yl]-4-hydroxy-2-methylbutanamide, Beta-secretase 1 Authors: Rondeau, J.-M. Deposit date: 2008-07-18 Release date: 2009-02-24 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors with activity in vivo. Bioorg.Med.Chem.Lett., 19, 2009
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2008-07-18
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