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The orphan nuclear receptor NR4A1 (Nur77, TR3) regulates oxidative and endoplasmic reticulum stress in pancreatic cancer cells

ChEBI2014-04-30 更新2026-07-21 收录

癌症分子机制

应激基因调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-46994 数据链接链接失效反馈

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资源简介：

The orphan nuclear receptor NR4A1 (Nur77, TR3) regulates oxidative and endoplasmic reticulum stress in pancreatic cancer cells

应用场景：

创建时间：

2014-04-30

癌症分子机制

表观遗传调控

K-Ras is frequently hyperactivated in human cancers through gain-of-function mutations that drive tumorigenesis. K-RasG12D, the most common oncogenic K-Ras allele, triggers massive transcriptomic and

NIAID Data Ecosystem40

Additional file 3 of ALKBH5 prevents hepatocellular carcinoma progression by post-transcriptional inhibition of PAQR4 in an m6A dependent manner

癌症分子机制

依赖性基因调控

Additional file 3. Overexpression of ALKBH5 decreased the proliferation capacity in 2 HCC cell lines, while co-overexpressed of PAQR4 reverted this phenomenon (A and B). Overexpression of ALKBH5 decre

NIAID Data Ecosystem30

DataSheet4_PRR11 promotes cell proliferation by regulating PTTG1 through interacting with E2F1 transcription factor in pan-cancer.zip

癌症分子机制

细胞周期调控

The upregulated proline rich 11 (PRR11) plays a critical role in cancer progression. The relevant biological functions of PRR11 in pan-cancer development are not well understood. In the current study,

NIAID Data Ecosystem30

miRNA expression signatures in multiple myeloma. miRNA expression signatures in multiple myeloma

多发性骨髓瘤miRNA表达

癌症分子机制

In the present study, miRNome profiling was carried out to investigate the microRNA expression patterns of multiple myeloma patients and to assess the pathogenetic role of differentially expressed miR

NIAID Data Ecosystem40

WTX overexpression effect on gastric cell line

癌症分子机制

肿瘤抑制基因

We used microarrays to detail the global gene expression in AGS gastric cancer cells overexpressing WTX, a tumor suppressor frequently inactivated in Wilms tumor. Results provide insight into roles fo

NIAID Data Ecosystem30

The orphan nuclear receptor NR4A1 (Nur77, TR3) regulates oxidative and endoplasmic reticulum stress in pancreatic cancer cells

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