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CD8+ T Cells Promote Maturation of Liver-Resident NK Cells via the CD70-CD27 axis

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NIAID Data Ecosystem2026-04-25 收录
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We discovered that LrNK cells exhibit a relatively immature phenotype and impaired cytotoxic capacity in the absence of CD8+ T cells. The provision of CD8+ T cells to Cd8-/- or Rag1-/- mice led to the restoration of LrNK cell maturation Overall design: LrNK and cNK mRNA profiles of wild type (WT) and CD8-/- mice were generated by deep sequencing, in triplicate, using Illumina

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2019-09-24
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