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Inward-occluded structure of human glycine transporter 2 bound to substrate glycine

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Protein Data Bank Japan2026-03-25 更新2026-04-19 收录
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https://pdbj.org/mine/summary/9r1h
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Inward-occluded structure of human glycine transporter 2 bound to substrate glycine Descriptor: CHLORIDE ION, GLYCINE, SODIUM ION, ... Authors: Cantwell Chater, R.P, Peiser-Oliver, J, Pati, T.K, Quinn, A.S, Lotsaris, I, Frangos, Z.J, Anderson, K.E, Tischer, A.E, Williams-Noonan, B.J, Aubrey, K.R, O Mara, M.L, Michaelides, M, Mohammadi, S.A, Cioffi, C.L, Vandenberg, R.J, Shahsavar, A. Deposit date: 2025-04-26 Release date: 2026-02-25 Last modified: 2026-03-25 Method: ELECTRON MICROSCOPY (3.02 Å) Cite: A reversible allosteric inhibitor of GlyT2 alleviates neuropathic pain without on-target side effects. Biorxiv, 2025
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2025-04-26
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