Distribution characteristics for the measured and estimated deviations.

The rows correspond to distributions of the estimated deviations with different sizes of subsets of those gene pairs used in the approximation process (see Figure 4). The distribution of the measured deviations ��ij is used as a references value for the different parameters (the first row). As robust measures of location (bias) and dispersion (variability), we calculated the trimmed mean and interquartile range, respectively, in addition to the median and median absolute deviation that were used in the previous comparative study [14]. The bold type indicates the subset size which provided the most accurate prediction of the functional links in terms of the area under the receiver operating characteristic curve (AUC).