RNA-Seq and miRNA-Seq of localized and locally advanced prostate cancer

Prostate cancer (PC) is one of the most common cancers among men worldwide, and advanced PCs, such as locally advanced PC (LAPC) and castration-resistant PC (CRPC), present the greatest challenges in clinical management. Current indicators have limited capacity to predict the disease course; therefore, better prognostic markers are greatly needed. In this project, we performed gene and microRNA expression profiling of localized and locally advanced prostate cancer using RNA-Seq/miRNA-Seq approach.