Crystal structure of human dCK complexed with clofarabine and ADP

Crystal structure of human dCK complexed with clofarabine and ADP Descriptor: 2-CHLORO-9-(2-DEOXY-2-FLUORO-B -D-ARABINOFURANOSYL)-9H-PURIN-6-AMINE, ADENOSINE-5'-DIPHOSPHATE, Deoxycytidine kinase, ... Authors: Zhang, Y, Secrist III, J.A, Ealick, S.E. Deposit date: 2005-07-05 Release date: 2006-01-24 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.55 Å) Cite: The structure of human deoxycytidine kinase in complex with clofarabine reveals key interactions for prodrug activation. Acta Crystallogr.,Sect.D, 62, 2006