Comprehensive Analysis of tsRNA Expression in Endometriosis using PANDORA-seq technology

Endometriosis is a common gynecological disease and there is no reliable non-invasive biomarker for its unknown pathogenesis. TsRNA is differentially expressed in a variety of cancers and is a new non-invasive biomarker. The aim of this study was to reveal the full landscape of tsRNA expression profile in endometriosis using PANDORA-seq, which will provide strong target support for early diagnosis and treatment. Overall design: PANDORA seq of Eutopic Endometric Tisses (EUs) and Ectopic Endometric Tisses (ECs) from the same patient with ovarian Endometriosis, as well as Eutopic Endometric Tisses (ENs) from control group patients.