Multivariate analyses of independent risk factors for a severe decline in the platelet count and severe thrombocytopenia during 3-day continuous veno-venous hemofiltration.

Adjusted factors include age, gender, APACHE II score, SOFA score, sepsis, hypotension, times of hemofilter clotting, anticoagulation, blood flow, dose, course of the disease and thrombocytopenia before CVVH. APACHE: acute physiology and chronic health Evaluation; AUROC: area under the receiver operating characteristic curve; CVVH: continuous veno-venous hemofiltration; OR = odds ratio.