ZNF384 fusion oncoproteins drive lineage aberrancy in acute leukemia [RNA-Seq]

RNA-seq of multiple models of ZNF384-rearrangments (transplanted human CD34 cells and transplanted mouse lineage negative cells) to determine differentially expressed genes. RNA-seq in GFP-sorted cells. CD34 cells had 5 fusion replicates and 1 wild type sample. ARF-null mouse tumors had at least 3 fusion replicates and 1 wild type sample. Mouse tumors had at least 2 fusion replicates, 3 NRAS G12D replicates, and 5 wild type replicates.