Dual Photoredox/Cobaloxime Catalysis for Cross-Dehydrogenative α‑Heteroarylation of Amines

We
report a dual-catalytic platform for the cross-dehydrogenative-coupling
between (benzo-)­thiazoles and amines which combines low loadings of
an iridium photoredox catalyst and a cobaloxime catalyst under blue
light irradiation. This transformation occurs without stoichiometric
oxidants, giving products in moderate to excellent yields. DFT calculations
support the key role of Co­(II) for rearomatization of the radical-addition
intermediate to generate the product.