RNA-seq of quadriceps muscle tissues from 10 months old, 30 months old, 30 months old calorie restricted, 30 months old rapamycin treated adult mice

We carried out RNA sequencing on the Quadriceps femoris muscle of 10 months old, 30 months old, 30 months old calorie restricted, 30 months old rapamycin treated. The treatments were started at the age of 15 months. The main goal of the study was to decipher the transcriptional changes in wild-type aging and upon above mentioned anti-aging treatments as well as to estimate the translation efficiency using ribo-seq and RNA-seq data.本研究对10月龄野生型、30月龄野生型、30月龄热量限制组以及30月龄雷帕霉素处理组的股四头肌开展了RNA测序（RNA-seq）。所有干预措施均于15月龄时启动。本研究的核心目标为阐明野生型衰老进程以及经上述抗衰老干预后的转录组变化，并结合核糖体测序（ribo-seq）与RNA-seq数据评估翻译效率。