Targeted brain metabolomics in two Lafora disease mouse models with or without PPP1R3C-deficiency
收藏Mendeley Data2026-04-09 收录
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https://data.mendeley.com/datasets/vv9n57g87g
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Targeted metabolomic profiles (protein-normalized relative abundances of brain metabolites) were obtained in two Lafora disease mouse models in the presence or absence of PPP1R3C (PTG). Genotypes and biological replicates are as follows: Cohort 1 WT1 (Epm2a+/+, Ppp1r3c+/+) n=9, LKO (Epm2a-/-, Ppp1r3c+/+) n=7, DKO1 (Epm2a-/-, Ppp1r3c-/-) n=10, PKO1 (Epm2a+/+, Ppp1r3c-/-) n=8; WT2 (Nhlrc1+/+, Ppp1r3c+/+) n=11, MKO (Nhlrc1-/-, Ppp1r3c+/+) n=9, DKO2 (Nhlrc1-/-, Ppp1r3c-/-) n=10, PKO2 (Nhlrc1+/+, Ppp1r3c-/-) n=6.
提供机构:
University of Texas Southwestern Medical School; University of Queensland; Hospital for Sick Children; University of Toronto



