Structure of PEDV main protease bound to potent broad-spectrum non-covalent inhibitor X77

Structure of PEDV main protease bound to potent broad-spectrum non-covalent inhibitor X77 Descriptor: MALONIC ACID, N-(4-tert-butylphenyl)-N-[(1R)-2-(cyclohexylamino)-2-oxo-1-(pyridin-3-yl)ethyl]-1H-imidazole-4-carboxamide, Peptidase C30 Authors: Mesecar, A.D, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2020-03-20 Release date: 2021-03-24 Last modified: 2026-04-22 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Broad-spectrum inhibition of coronavirus main and papain-like proteases by HCV drugs Res Sq, 2026