five

Position 45 influences the peptide binding motif of HLA-B*44:08.

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https://immunedata.org/display-item.php?repository=0009&id=AWPT2O0ah18v6WY6OqZA&query=%20
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Peptides eluted from soluble HLA-B*44:08 obtained from LCL 721.221 cells were compared with known peptides from HLA-B*44:02. HLA-B*44:02 has an anchor motif of E at the p2 anchor position, while HLA-B*44:08 was found to exhibit Q and L as anchor motif residues. The position 45 Met/Lys polymorphism between HLA-B*44:08 and HLA-B*44:02 thus contributes to the alteration in the peptide binding.
提供机构:
IEDB
创建时间:
2012-01-01
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