Single-cell sequencing screening of biomarkers associated with Lipophagy in the MPTP model mice of Parkinson's disease
收藏Figshare2024-08-15 更新2026-04-08 收录
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https://figshare.com/articles/dataset/Single-cell_sequencing_screening_of_biomarkers_associated_with_Lipophagy_in_the_MPTP_model_mice_of_Parkinson_s_disease/26724526/1
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资源简介：
MPTP model mice brains (PD, n=3; CON, n=3) underwent scRNA-seq. Post-QC, cells were clustered & annotated. Differential infiltrated cells (DICs) identified between PD & CON. DICs further sub-clustered. DIC-DEGs & DE-LRGs determined. Overlapping DIC-DEGs & DE-LRGs yielded candidate genes. CytoNCA's 5 algorithms screened biomarkers. Biomarker expression compared between PD & CON. Cell-cell communication & pseudotime analyses explored communication & differentiation.
提供机构：
Liu, Mei-jun; Han, Shi-yu; Yang, Dong-dong; Zhu, Si-jia
创建时间：
2024-08-15
