Crystal structure of SARS-CoV-2 main protease (MPro) in complex with the non-covalent inhibitor GA-17S
收藏Protein Data Bank Japan2024-01-31 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/8acd
下载链接
链接失效反馈官方服务：
资源简介：
Crystal structure of SARS-CoV-2 main protease (MPro) in complex with the non-covalent inhibitor GA-17S Descriptor: (2~{S})-4-[[2,4-bis(oxidanylidene)-1~{H}-pyrimidin-6-yl]carbonyl]-1-(3,4-dichlorophenyl)-~{N}-(thiophen-2-ylmethyl)piperazine-2-carboxamide, 3C-like proteinase nsp5 Authors: Strater, N, Muller, C.E, Sylvester, K, Claff, T, Weisse, R.H, Gao, S, Tollefson, A.E, Liu, X, Zhan, P. Deposit date: 2022-07-05 Release date: 2022-09-28 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.39 Å) Cite: Discovery and Crystallographic Studies of Trisubstituted Piperazine Derivatives as Non-Covalent SARS-CoV-2 Main Protease Inhibitors with High Target Specificity and Low Toxicity. J.Med.Chem., 65, 2022
创建时间：
2022-07-05
