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APS1 and celiac patients reveal autoimmune amelogenesis imperfecta

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE224247
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To investigate the dependence of amelogenesis imperfecta-related gene expression and ameloblast-related gene expression on Aire in the thymus, mTEChi from Aire+/+ and Aire-/- were sorted and subjected to bulk RNAseq. mRNA profiles of mature medullary thymic epithelial cells (mTEChi) from young (4.5 weeks old) NOD.Aire-/- mice ,were generated by deep sequencing, using the MARSseq method.
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2024-01-05
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