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ChIP-seq for TCF7L2/TCF4 in E16.5 intestinal epithelial cells

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https://www.ncbi.nlm.nih.gov/sra/SRP300888
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As part of our comprehensive characterization of intestinal development, we performed ChIP-seq for TCF7L2/TCF4 in mouse E16.5 intestinal epithelial cells. We identified more than 6000 regions bound by TCF7L2/TCF4 including a binding site in an enhancer driving Shh expression. Combined with transcriptional and functional analyses, our data reveal a novel cross-talk between WNT and Hedgehog signaling pathways. Overall design: ChIP-seq for TCF7L2/TCF4 in E16.5 intestinal epithelial cells
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2023-09-13
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