Thermostabilised full length human mGluR5-5M with orthosteric antagonist, LY341495
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Thermostabilised full length human mGluR5-5M with orthosteric antagonist, LY341495 Descriptor: 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 5 Authors: Vinothkumar, K.R, Cannone, G, Lebon, G. Deposit date: 2021-07-16 Release date: 2021-09-08 Last modified: 2024-11-13 Method: ELECTRON MICROSCOPY (4 Å) Cite: Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations. Cell Rep, 36, 2021
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2021-07-16
