遇见数据集

FUMA results for disease-predominant loci across Alzheimer's disease, Parkinson's disease and Lewy body dementia

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Zenodo2026-06-16 更新2026-06-17 收录
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This dataset contains processed, summary-level FUMA v1.3.7 and MAGMA v1.08 output files generated from original and GCTA-mtCOJO-conditioned GWAS summary statistics for Alzheimer's disease, Parkinson's disease, and Lewy body dementia. The files support the manuscript Disease-predominant loci across Alzheimer's disease, Parkinson's disease and Lewy body dementia: evidence from the UK Biobank prospective cohort, conditional GWAS and colocalization. The archive includes FUMA genomic risk loci, lead SNPs, independent significant SNPs, mapped SNPs and genes, linkage-disequilibrium SNPs, chromatin-state/CADD annotations, ANNOVAR annotations, GWAS Catalog overlaps, MAGMA gene and gene-set analyses, GTEx v8 tissue-expression enrichment outputs, FUMA run parameters, and selected author-derived conditional lead-SNP supporting tables. It does not contain individual-level genotype, phenotype, or UK Biobank participant data. Access to UK Biobank data is controlled by UK Biobank application ID 249728. Original GWAS summary statistics were obtained from the IGAP, IPDGC, and published LBD GWAS resources described in the manuscript.

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Zenodo
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2026-06-16
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