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Human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and Leucettine L41

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Protein Data Bank Japan2023-09-13 更新2026-03-21 收录
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Human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and Leucettine L41 Descriptor: 1,2-ETHANEDIOL, 5-(1,3-benzodioxol-5-ylmethyl)-2-(phenylamino)-4H-imidazol-4-one, Consensus peptide (Pimtide), ... Authors: Filippakopoulos, P, Bullock, A, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A, Meijer, L, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2012-09-01 Release date: 2012-10-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Selectivity, cocrystal structures, and neuroprotective properties of leucettines, a family of protein kinase inhibitors derived from the marine sponge alkaloid leucettamine B. J.Med.Chem., 55, 2012
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2012-09-01
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