Clustering (C), characteristic path length (L), modularity (Q), global efficiency (Eglob), local efficiency (Eloc) and small-worldness () parameters obtained for the brain anatomical networks of control and shiverer mice groups.

For each measure and fiber tracking algorithm, mean values are reported with their corresponding standard errors (i.e. the uncertainty of how the sample mean represents the underlying population mean). For each measure, the multivariate permutation P-value corresponds to the null hypothesis that means of obtained group values are equal (a P-value near to zero, i.e. PC, Q, Eglob, Eloc and (all PL (PTable S2. Significant P values are depicted in bold type.