Next generation sequencing for lncRNA profile of bone marrow mesenchymal stem cells through establishing exercise rat model by treadmill running experiment

In this study, we proved the exercise-induced promotion of osteogenic differentiation and inhibition of adipogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) through establishing exercise animal model by treadmill running experiment. lncRNA sequencing analysis identified 44 upregulated lncRNAs and 39 downregulated lncRNAs in exercise group. Examination of and lncRNA profile in bone marrow mesenchymal stem cells (BMSCs) of two model.