Patients Utilized in Study.

1Samples were provided coded from St. Louis University Medical School.
2,3HCC or cirrhosis was determined by MRI or by liver biopsy.
4Patients classified as HBV only were defined as those with HBsAg positivity but no evidence of liver cirrhosis.
5Patients classified as HCV only were defined as those with HCV RNA positivity but no evidence of liver cirrhosis.
6OLD, including cryptogenic liver disease, alcohol induced liver disease, nonalcoholic steatohepatitis, and autoimmune hepatitis.
7Patients without any evidence of liver disease were used as controls.
8Etiology: HBV, hepatitis B virus; HCV, hepatitis C virus; crypto, cryptogenic liver disease; alcohol, alcohol induced liver disease; other, liver disease of unknown origin.
9MELD: Model for end stage liver disease.
10The percent of patients with each Child-Pugh score is given as a percentage in each group.
11Tumor staging was determined using the United Network of Organ Sharing-modified TNM staging system for HCC. The percent of patients within each stage is given. NA, not available.
HBV, hepatitis B virus; HCC, hepatocellular carcinoma; HCV, hepatitis C virus; MELD, model for end stage liver disease; OLD, other liver disease.