Results of region-of-interest (ROI) analyses of the ROI hippocampus + parahippocampal gyrus bilaterally.

Contrasts: A) MDD patients (n = 132) versus healthy controls (n = 132), B) patients with first depressive episode (n = 35) versus healthy controls (n = 35), C) patients with recurrent depressive episodes (n = 97) versus healthy controls (n = 97) and D) patients with first depressive episode (n = 35) versus patients with recurrent depressive episodes (n = 97). Analyses where conducted at pROI: region of interest.MDD: major depressive disorder.Con: controls; Pat: patients.L: left; R: right.