Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX. Homo sapiens
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA183941
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资源简介:
Idax/Cxxc4 is the CXXC domain protein that preferentially binds unmethylated CpG sites in vitro. By performing genome-wide mapping of Idax/Cxxc4, we report here that Idax is preferentially enriched in CpG-rich regions in genome including the promoters containing CpG islands. Overall design: ChIP-seq binding site detection of Myc-Idax and Myc-IdaxDBM over cells expressing an empty vector in stable HEK293T cell lines; two replicates per condition (2x ChIP Myc-Idax, 2x ChIP Myc-IdaxDBM, 2xChIP empty vector)
创建时间:
2012-12-17



