Tracking antigen-specific T cell response to cancer immunotherapy

peptide_vaccination.zip contains TCRb clonotypes for mices which was vaccinated by 14 peptides. Samples are describes in metadata : SupplementTable1_metadata.xlsx. Infromation about peptides contains in Table_1_peptides.xlsx.SupplementTable2_SamplesClusters : matrix, presentes cuumulative frequency of each cluster between samples.SupplementTable3_clusters : produced dataset of helper T cells (Th) TCR beta CDR3s specific to B16 melanoma neoantigens in the I-Ab pMHCII contextCTLA4_treatment.zip : dataset with TCRb clonotypes of dLNs and ndLNs of CTLA-4 treated and control mice, metadata inside.