CRCNS.org pfc-7

This dataset contains single unit recordings made from several different subregions of prefrontal cortex in 2 macaque monkeys (dorsolateral prefrontal cortex; orbitofrontal cortex; anterior cingulate cortex) performing an information search and decision-making task. Some of the neurons are simultaneously recorded across the different areas (during a typical recording session 8-24 electrodes were lowered simultaneously, see supplementary Table S1 in Hunt/Malalasekera et al., 2018). In the paper, we stack condition-averaged responses across the population to create pseudopopuluations, which reveal the distinct contributions of each PFC subregion to information search and reward-guided choice. Results from the experiments are described in: Triple dissociation of attention and decision computations across prefrontal cortex Laurence T. Hunt*, W.M. Nishantha Malalasekera*, Archy O. de Berker, Simon F. Farmer, Timothy E. J. Behrens and Steven W. Kennerley Nature Neuroscience in press (2018) doi: to be confirmed本数据集包含两只恒河猴在执行信息搜索与决策任务时，其前额叶皮层（prefrontal cortex）多个不同亚区的单神经元放电记录，所涉脑区包括背外侧前额叶皮层（dorsolateral prefrontal cortex）、眶额叶皮层（orbitofrontal cortex）以及前扣带回皮层（anterior cingulate cortex）。部分神经元可在多个脑区同时被记录——在典型的记录会话中，会同时插入8至24根电极，相关细节参见Hunt与Malalasekera等人2018年发表的补充表S1。在该研究中，我们将群体神经元的条件平均响应进行堆叠，以此构建伪群体（pseudopopulations），进而揭示各前额叶皮层亚区在信息搜索与奖励导向选择中各自的独特作用。本实验的相关研究结果详见论文：《前额叶皮层注意力与决策计算的三重分离》（Triple dissociation of attention and decision computations across prefrontal cortex），作者为Laurence T. Hunt*、W.M. Nishantha Malalasekera*、Archy O. de Berker、Simon F. Farmer、Timothy E. J. Behrens与Steven W. Kennerley，刊载于《自然-神经科学》（Nature Neuroscience）2018年待刊（doi待确认）。

搜集汇总

背景与挑战

背景概述

CRCNS.org pfc-7数据集记录了猕猴前额叶皮层三个亚区在信息搜索和选择任务中的神经活动数据，由Hunt L.T.、Malalasekera W.M.N和Kennerley S.W.贡献。该数据集属于CRCNS项目的前额叶皮层系列，专注于计算神经科学研究中的数据共享，用于分析决策过程中的神经机制。