90-day mortality in AKI-D and CKD5-D patients admitted to the ICU

Acute kidney injury (AKI) and chronic kidney disease (CKD) are related conditions commonly encountered in intensive care. While both may require renal replacement therapy (RRT), critically ill patients with dialysis-requiring AKI have significantly higher mortality and poor clinical outcomes than those with end-stage CKD. To compare 90-day mortality between patients with KDIGO stage 3 dialysis-requiring AKI (AKI-D) and those with stage 5 dialysis-dependent CKD (CKD5-D) admitted to the ICU. Secondary objectives were to identify independent predictors of increased 90-day mortality among AKI-D and CKD5-D patients, and to identify independent predictors of RRT at 90 days among patients who experienced an episode of AKI-D. This retrospective, single-center cohort study included adult patients with AKI-D or CKD5-D admitted to the ICU of a private quaternary hospital in São Paulo, Brazil. The study was approved by the Research Ethics Committee (CEP) of the Federal University of São Paulo,..., Study Design
This was a retrospective, single-center cohort study approved by the Research Ethics Committee (CEP) of the Federal University of São Paulo – UNIFESP (CAAE: 27698819300005505), with a waiver of informed consent. This study is reported in accordance with the Strengthening the Reporting of Observational studies in Epidemiology (STROBE) statement.
Setting
The study was conducted in the Adult Intensive Care Unit (ICU) of Einstein Hospital Israelita, a private quaternary care hospital located in São Paulo, Brazil. At the time of the study, the general ICU had 41 beds and provided care to both clinical and surgical patients. Through a partnership with the Brazilian Ministry of Health (Sistema Único de Saúde [SUS]), the ICU also managed patients involved in solid organ transplantation programs, including transplant candidates, those on waiting lists, and recipients of kidney, liver, lung, heart, pancreas, and multivisceral transplantation.
Study participants
Adult patients who und..., # 90-day mortality in AKI-D and CKD5-D patients admitted to the ICU

Dataset DOI: [10.5061/dryad.sqv9s4nht](https://doi.org/10.5061/dryad.sqv9s4nht)

## Description of the data and file structure

**90-DAY MORTALITY IN AKI-D AND CKD 5-D PATIENTS ADMITTED TO THE ICU**

**File structure**

The de-identified data bank presented here has been used for the analyses reported in the manuscript \"90-day mortality in AKI-D and CKD 5-D patients admitted to the ICU.\" The file contains baseline characteristics (age, gender, race), comorbidities, rrt characteristics, and ICU and hospital stay characteristics. To maintain data anonymization, time-related variables (namely, ICU length of stay and hospital length of stay) have been modified using random noise to reduce their identifiability while preserving their analytical utility. Additionally, to mask the identification of patients, their age has been categorized according to the interquartile range. Some data points may be missing due to incomplete ..., The study was approved by the Research Ethics Committee (CEP) of the Federal University of São Paulo, with a waiver of informed consent. Our research was conducted on human data in compliance with the Helsinki Declaration.