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Transcriptome profile after knockdown of a lncRNA EPEL in A549 lung cancer cells

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE102356
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Analysis of regulation of a lncRNA EPEL at gene expression level. The hypothesis tested in the present study is that EPEL regulates proliferation of lung cancer cells through up-regulation of E2F target genes. Results provide important information of the response of EPEL knockdown such as up-regulation of specific cell cycle-related E2F genes and the cellular functions. Total RNA samples were isolated from A549 lung cancer cells after treating with siRNAs for EPEL or a non-targeting control siRNA. The cRNA libraries were prepared from the total RNA samples, hybridized to the HumanHT-12 gene expression beachip (Illumina).
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2021-07-25
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