Interrelationships between replication infidelity and genome composition

Alliance of Genome Resources2026-08-01 收录

复制错误与基因组进化

基因组不稳定性

数据链接：

https://www.yeastgenome.org/dataset/GSE56939 数据链接链接失效反馈

官方服务：

资源简介：

An enduring issue in evolutionary and cancer biology is how replication infidelity influences genome composition and vice versa

Chromothripsis is a frequent event and underlies typical genetic changes in early T-cell precursor lymphoblastic leukemia in adults [RNA-seq]

白血病分子机制

基因组不稳定性

Chromothripsis is a mitotic catastrophe that arises from multiple double strand breaks and incorrect re-joining of one or a few chromosomes. We report on incidence, distribution, and features of chrom

NIAID Data Ecosystem60

Mycobacterium tuberculosis promotes genomic instability in macrophages

分枝杆菌

基因组不稳定性

BACKGROUND Mycobacterium tuberculosis is an intracellular pathogen, which may either block cellular defensive mechanisms and survive inside the host cell or induce cell death. Several studies are stil

DataCite Commons2020-08-30 更新40

Table2_Novel GIRlncRNA Signature for Predicting the Clinical Outcome and Therapeutic Response in NSCLC.xlsx

癌症预后预测

基因组不稳定性

Background: Non–small cell lung cancer (NSCLC) is highly malignant with driver somatic mutations and genomic instability. Long non-coding RNAs (lncRNAs) play a vital role in regulating these two aspec

NIAID Data Ecosystem20

Data_Sheet_1_Genome Instability-Derived Genes Are Novel Prognostic Biomarkers for Triple-Negative Breast Cancer.docx

三阴性乳腺癌

基因组不稳定性

BackgroundTriple-negative breast cancer (TNBC) is an aggressive disease. Recent studies have identified genome instability-derived genes for patient outcomes. However, most of the studies mainly focus

NIAID Data Ecosystem40

Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent-strand DNA

复制叉保护机制

基因组不稳定性

Degradation and collapse of stalled replication forks are main sources of genomic instability, yet the molecular mechanisms for protecting forks from degradation/collapse are not well understood. Here

NIAID Data Ecosystem40

Interrelationships between replication infidelity and genome composition

资源简介：

相关数据集