Supplementary Data from A Genome-Wide Association Study Identifies Two Novel Susceptible Regions for Squamous Cell Carcinoma of the Head and Neck

Supplementary Tables 1-4, 9-16. Supplemental Table 1. Association results of SNPs with SCCHN risk with P-value {less than or equal to} 1x10-3 in the discovery dataset or with P-value {less than or equal to} 5x10-8 in the meta-analysis. Supplemental Table 2. Association results of SNPs with oral cancer risk with P-value {less than or equal to} 1x10-3 in the discovery dataset or with P-value {less than or equal to} 5x10-8 in the meta-analysis. Supplemental Table 3. Association results of SNPs with oropharynx cancer risk with P-value {less than or equal to} 1x10-3 in the discovery dataset or with P-value {less than or equal to} 5x10-8 in the meta-analysis. Supplemental Table 4. Association results of SNPs with hypopharynx and larynx cancer risk with P-value {less than or equal to} 1x10-3 in the discovery dataset or with P-value {less than or equal to} 5x10-8 in the meta-analysis. Supplemental Table 9. Association results of previously reported SNPs in the discovery dataset. Supplemental Table 10. Association results of HLA variants with overal SCCHN cancer risk with P-value {less than or equal to} 0.05 in the MDACC data. Supplemental Table 11. Association results of HLA variants with oral cancer risk with P-value {less than or equal to} 0.05 in the MDACC data. Supplemental Table 12. Association results of HLA variants with oropharyngeal cancer risk with P-value {less than or equal to} 0.05 in the MDACC data. Supplemental Table 13. Association results of HLA variants with hypo-pharyngeal and laryngeal cancer risk with P-value {less than or equal to} 0.05 in the MDACC data. Supplemental Table 14. Associations of DRB1*1301-DQA1*0103-DQB1*0603 haplotype with the risks of SCCHN and subtyp tumors. Supplementary Table 15. Correlations between standardized polygenic risk score (PRS) and the risk of oropharyngeal cancer risk in the MDACC study and OncoArray study. Supplementary table 16. Function prediction for SNPs with validated P {less than or equal to} 0.05 and meta-analysis P-value {less than or equal to} 5x10-8 with Haploreg 4.1.