Dose response functions used by disease and for all-cause mortality.

1. Methods for estimating exposures and selection of relative risks are reported in Woodcock et al 2009 [2]. Transformation of exposure for specific diseases is reported here for the main model (alternative transformations 0.25, 0.375, log, and 1 were used in sensitivity analysis.2. 0.72 for 3 hours per week of cycling at 14 km/hour.3. 0.78 29 minutes per day of walking at 4.8 km/hour.4. Reduction in health outcome as a change in walking or cycling = 1 – RR ∧ (a/b).a = Scenario MET hours per weeks∧ Transformation of exposure.b = Reference MET hours per week ∧ Transformation of exposure.