Comprehensive proteomics analysis methods: Pre-Invasive Serous Lesions of the Endometrium and Fallopian Tube analyzed and compared

We present data from precancerous lesions from the endometrium and fallopian tube of a single patient. Using this complimentary approach, we gained a spatially defined representation of the molecular landscape within these tissue sections, and identified hundreds of proteins within the precancerous, and neighboring healthy regions. The method presented here represent a useful tool to maximize the amount of molecular data acquired from small sample sizes and even single cases, as shown here. Our initial data are indicative of a migratory phenotype in these lesions and warrant further research into their malignant capabilities.