The crystal structure of Human VPS34 in complex with a selective and potent inhibitor
收藏Protein Data Bank Japan2024-03-06 更新2026-03-21 收录
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The crystal structure of Human VPS34 in complex with a selective and potent inhibitor Descriptor: 1-[[4-(cyclopropylmethyl)-5-[2-(pyridin-4-ylamino)pyrimidin-4-yl]pyrimidin-2-yl]amino]-2-methyl-propan-2-ol, GLYCEROL, Phosphatidylinositol 3-kinase catalytic subunit type 3, ... Authors: Kearney, E.P. Deposit date: 2015-11-09 Release date: 2016-11-16 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Potent, selective, and orally bioavailable inhibitors of VPS34 provide chemical tools to modulate autophagy in vivo To Be Published
创建时间:
2015-11-09



