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Crystal structure of DNPH1 bound by compound 31.

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Protein Data Bank Japan2025-12-10 更新2026-04-19 收录
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Crystal structure of DNPH1 bound by compound 31. Descriptor: 3-[2-fluoranyl-3-(trifluoromethyl)phenyl]-4-[[4-(methylamino)-6-propan-2-yl-quinazolin-2-yl]amino]benzoic acid, 5-hydroxymethyl-dUMP N-hydrolase Authors: Collie, G.W. Deposit date: 2025-01-27 Release date: 2025-11-12 Last modified: 2025-12-10 Method: X-RAY DIFFRACTION (1.213 Å) Cite: Discovery and Optimization of a Non-Nucleoside-Based Series of Inhibitors of 2'-Deoxynucleoside 5'-Monophosphate Glycosidase (DNPH1). J.Med.Chem., 68, 2025
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