Summary Statistics from "Meta-GWAS of PCSK9 levels detects two novel loci at APOB and TM6SF2"

GWAMA summary statistics of PCSK9 levels using fixed-effect model. Genome-wide data is given for Europeans with statin adjustment and Europeans without statin treatment only (subset of the population). In addition, locus-wide data of the PCSK9 gene locus for African-Americans without statin treatment is listed.

When using this data, please cite: Pott J, Gadin J, Theusch E, et al.. Meta-GWAS of PCSK9 levels detects two novel loci at APOB and TM6SF2. Hum Mol Genet. 2021 Sep 30:ddab279. doi: 10.1093/hmg/ddab279. PMID: 34590679

All txt files contain the following columns:

markername

chr

bp_hg19 (base position according to hg19)

ea (effect allele)

oa (other allele)

eaf (effect allele frequency)

info (minimal info score across all used studies)

nSamples (sample size per SNP)

nStudies (number of studies)

beta (effect estimate)

se (standard error)

p (p-value)

I2 (SNP heterogeneity across studies)

phenotype (phenotyp setting)