cryo-EM structure of human Gastric inhibitory polypeptide receptor GIPR bound to tirzepatide
收藏Protein Data Bank Japan2026-03-04 更新2026-03-28 收录
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cryo-EM structure of human Gastric inhibitory polypeptide receptor GIPR bound to tirzepatide Descriptor: 2-fluoro-4-[(1R)-6-methoxy-1-methyl-2-{(1S)-1-[4-(propan-2-yl)phenyl]ethyl}-1,2,3,4-tetrahydroisoquinolin-5-yl]-6-[(2-methylpropyl)amino]phenol, Gastric inhibitory polypeptide receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Sun, B, Kobilka, B.K, Sloop, K.W, Feng, D, Kobilka, T.S. Deposit date: 2021-07-06 Release date: 2022-04-13 Last modified: 2026-03-04 Method: ELECTRON MICROSCOPY (3.08 Å) Cite: Structural determinants of dual incretin receptor agonism by tirzepatide. Proc.Natl.Acad.Sci.USA, 119, 2022
创建时间：
2021-07-06
