Single-cell transcription and chromatin accessbility profiles of IDH mutant gliomas

we use single cell RNA-seq and ATAC-seq to understand the cell states and epigenetic states of IDH mutant gliomas, including the condition with DNMT1 inhibitor treatment Primary IDH mutant glioma samples are collected after surgery and used for the establishment of organoid. Dissociated tumors are used for scRNA-seq and scATA-seq assays from 10x genomics. **'Submitter declares that the raw data will be deposited in dbGaP due to patient privacy concerns.***