遇见数据集

CAPN2: A Target Enabling Package

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Zenodo2025-03-10 更新2026-05-26 收录
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CAPN2 mediates neurodegenerative effect through cleavage of a range of proteins linked to tau hyperphosphorylation (GSK-3β), higher levels of Aβ (NCX3), or poor memory (CPEB3). Inhibiting calpain-2 might reduce cleavage of these proteins and reverse its neurodegenerative effect. This aim of this TEP is to produce reagents to allow for further analysis of CAPN2 as a potential target for AD treatment.

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Zenodo
创建时间:
2025-03-10
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