Mother of unification studies, a 204-subject multimodal neuroimaging dataset to study language processing

The Mother Of Unification Studies (MOUS) dataset contains multimodal neuroimaging data that has been acquired from 204 healthy human subjects. The neuroimaging protocol consisted of magnetic resonance imaging (MRI) to derive information at high spatial resolution about brain anatomy and structural connections, as well as functional data during task, and at rest. In addition, magnetoencephalography (MEG) was used to obtain high temporal resolution electrophysiological measurements during task, and at rest. All subjects performed a language task, during which they had to process linguistic utterances that either consisted of normal or scrambled sentences. Half of the subjects were reading the stimuli, the other half listened to the stimuli. The resting state measurements consisted of 5minutes eyes-open for the MEG and 7 minutes eyes-closed for fMRI. The neuroimaging data, as well as the information about the experimental events are shared according to the Brain Imaging Data Structure (BIDS) format. This unprecedented neuroimaging language data collection allows for the investigation of various aspects of the neurobiological correlates of language.

统一研究母数据集（Mother Of Unification Studies, MOUS）包含204名健康人类受试者的多模态神经影像学数据。该数据集的神经影像学实验方案涵盖磁共振成像（MRI）与脑磁图（MEG）两类模态：其中磁共振成像（MRI）用于采集大脑解剖结构与结构连接的高空间分辨率信息，以及任务态与静息态功能数据；脑磁图（MEG）则用于获取任务态与静息态下的高时间分辨率电生理测量数据。所有受试者均完成一项语言任务，需处理正常语序或语序打乱的语言语句，其中半数受试者通过阅读接收刺激材料，另一半则通过聆听接收刺激材料。静息态测量环节中，脑磁图（MEG）的采集时长为5分钟睁眼状态，功能磁共振成像（fMRI）则为7分钟闭眼状态。所有神经影像学数据及实验事件相关信息均按照脑成像数据结构（BIDS）格式进行共享。此项前所未有的语言相关神经影像学数据集合，可为语言相关神经生物学机制的多维度研究提供支撑。