Co-crystal structure of TNKS1 with compound 18 [4-[(4S)-5,5-dimethyl-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-N-(quinolin-8-yl)benzamide]
收藏Protein Data Bank Japan2024-02-28 更新2026-03-21 收录
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Co-crystal structure of TNKS1 with compound 18 [4-[(4S)-5,5-dimethyl-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-N-(quinolin-8-yl)benzamide] Descriptor: 4-[(4S)-5,5-dimethyl-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-N-(quinolin-8-yl)benzamide, Tankyrase-1, ZINC ION Authors: Huang, X, Bregman, H, Wilson, C, DiMauro, E, Gunaydin, H. Deposit date: 2013-04-12 Release date: 2013-06-05 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Discovery of novel, induced-pocket binding oxazolidinones as potent, selective, and orally bioavailable tankyrase inhibitors. J.Med.Chem., 56, 2013
创建时间：
2013-04-12
