遇见数据集

KrasG12D partially compensates for the loss of beta-catenin in MLL-AF9 AML

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NIAID Data Ecosystem2026-03-10 收录
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The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in MLL-AF9 AML. We evaluated the dependance on beta-catenin for KrasG12DMLL-AF9 leukemia. Lin-Kit+ bone marrow cells obtained from mice transplanted with primary MLL-AF9 leukemia cells and KRasG12DMLL-AF9 leukemia cells were assessed for gene expression in the presence or absence of beta-catenin

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2019-02-11
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