GNPS - Cardiomyocyte-specific NAMPT Knockout Mice: Metabolomics of Heart Ventricle Tissues at 2-weeks Post-Deletion

Metabolomics from heart ventricular tissues of wild-type (WT) and cardiomyocyte-specific conditional NAMPT knockout (cNKO) mice untreated or treated with nicotinamide riboside (cNKO-NR), harvested at 2-weeks post-NAMPT deletion (post-tamoxifen). For untargeted metabolomic running, mass spectrometer was operated in both negative (NEG, 70 to 1000 m/z) and positive (POS, 50 to 117.9 m/z) ion mode with the HILIC 25-minute method for the detection of metabolites. For targeted metabolomic running, mass spectrometer was operated in two positive-mode scans (SCAN1 at 118.5 to 800 m/z and SCAN2 at 70 to 117.5 m/z) with the HILIC 20-minute method for the detection of NAD derivatives.