AlzPathway

AlzPathway is a publicly available pathway map that comprehensively catalogs all signaling pathways in the field of Alzheimer's disease (AD).AlzPathway is composed by thousands of molecules and reactions in neuron, brain blood barrier, presynaptic, postsynaptic, astrocyte, and microglial cells and their cellular localizations. AlzPathway is the comprehensive map of all intra, inner and extra cellular AD signalings for deciphering pathogenesis of AD.AlzPathway是一款公开可获取的通路图谱，可全面收录阿尔茨海默病（Alzheimer's Disease, AD）领域内的全部信号通路。该数据集由数千个分子与反应过程组成，覆盖神经元、血脑屏障（blood-brain barrier）、突触前、突触后、星形胶质细胞以及小胶质细胞等各类细胞与结构及其细胞定位。AlzPathway囊括了阿尔茨海默病所有细胞内、膜内及细胞外信号通路，旨在解析阿尔茨海默病的发病机制。

搜集汇总

背景与挑战

背景概述

AlzPathway是一个公开可用的通路图，全面收录了阿尔茨海默病（AD）领域的所有信号通路。它基于手动整理的综述文章构建，涵盖神经元、血脑屏障等多种细胞类型中的分子和反应，旨在解码AD的发病机制。