High-frequency (100 kHz) rectangular bipolar pulses stimulation of individual hippocampal neurons: the effect of electric field

This dataset includes recordings of hippocampal neurons stimulated at 100 kHz under various amplitudes (measured as one polarity, V; the peak-to-peak value would be double this amount). Rectangular bipolar pulses were applied continuously for 2 seconds, beginning at 25 ms, with a 50% duty cycle. The pulse amplitude was constant at the indicated voltage. For the electrode configuration used, 1V corresponds to 36 V/cm. Neuron action potentials were visualized using the voltage-sensitive fluorescent dye, FluoVolt. This study was partially supported by NIH grant 15R21EY034803.