Collaborative Cohort of Cohorts for COVID-19 Research (C4R): Multi-Ethnic Study of Atherosclerosis (MESA)

<u>**Cohort Description **</u>

The Multi-Ethnic Study of Atherosclerosis (MESA) is a study of the characteristics of subclinical cardiovascular disease (CVD) and the risk factors that predict progression to clinically overt CVD or progression of the subclinical disease. MESA researchers study a diverse, population-based sample of 6,814 asymptomatic men and women aged 45-84. Participants were recruited from six field centers across the United States: Wake Forest University, Columbia University, Johns Hopkins University, University of Minnesota, Northwestern University and University of California - Los Angeles.

Participants of this study are limited to MESA Classic participants. MESA Family and MESA Air Pollution cohorts are excluded from C4R.

<u>**Data Being Submitted **</u>
- Wave 1 questionnaire data includes 397 variables for up to 3119 MESA participants in C4R. - Wave 2 questionnaire data includes 448 variables for up to 1933 MESA participants in C4R. - Dried Blood Spot/Serosurvey data includes 7 variables for up to 1058 MESA participants in C4R. - Derived data includes 43 variables for up to 3283 MESA participants in C4R. - Phenotype data includes 113 variables for up to 3136 MESA participants in C4R.