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PAF1 Drives Pancreatic Cancer Oncogenesis by Promoting Stemness via PHF5A/DDX3 Sub-complex (RNA-seq)

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NIAID Data Ecosystem2026-03-11 收录
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In this study, we established that PAF1 is critical for pancreatic tumorigenesis, and CSC-driven tumor maintenance because depletion of PAF1 resulted in significantly less tumor burden and reduction in CSC populations. Overall design: SW1990 side population control and PAF1 CRISPR KD cells were subjected to RNA sequencing

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2020-02-05
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